CAS No.4474-91-3

Chemical Name:ANGIOTENSIN II, HUMAN

SynonymsANGIOTENSIN II;Ang II;DRVYIHPF;TY-10721;AngiotensinⅡ;ANGIOTENSIN-2;H-DRVYIHPF-OH;angiotensin renin;ANTI-ANGIOTENSIN II;ile(5)-angiotensini

CBNumber:CB0338057

Molecular Formula:C50H71N13O12

Molecular Weight:1046.2

Boiling point 809.08°C (rough estimate)

Density 1.1257 (rough estimate)

refractive index 1.6700 (estimate)

RTECS BW2165000

storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility insoluble in DMSO; insoluble in EtOH; ≥100.2 mg/mL in H2O

Description

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two distinct receptors, AT1 and AT2, each evoking distinct signaling pathways and physiological responses. The development of antagonists for specific angiotensin II receptor subtypes represents a valuable alternative to ACE inhibitors.

Uses

Cardiopulmonary resuscitation - not yet an approved application

Uses

A peptide involved in the regulation of blood pressure

Uses

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two distinct receptors, AT1 and AT2, each evoking distinct signaling pathways and physiological responses. The development of antagonists for specific angiotensin II receptor subtypes represents a valuable alternative to ACE inhibitors.